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Toxicity and biodegradation of the pharmaceutical diclofenac employing the green marine microalga Tetraselmis sp.: A preliminary study

IWRA 2023 Online Conference - Emerging Pollutants: Protecting Water Quality for the Health of People and the Environment
Theme 5: PRIORITY emerging pollutants in the hydrocycle: microplastics, nanomaterial, PFAs and PPCPs
Author(s): Silvia Pedroso Melegari, Center for Marine Studies Federal University of Parana – UFPR

Silvia Pedroso Melegari, Center for Marine Studies Federal University of Parana – UFPR


Oral: PDF

Abstract

INTRODUCTION

Environmental pollution by emerging contaminants (pharmaceuticals) and their toxic effects on aquatic organisms.

 

MAIN GOALS OF THE STUDY

  • Contribute to the advances on toxicology fields and biodegradation technologies;
  • Contribute with data of a potential green alternative for degradation of emerging contaminants.

 

OBJECTIVES

  • Evaluate the toxicity of the anti-inflammatory sodium diclofenac (DCF) on the marine microalgae Tetraselmis sp.;
  • Evaluate the potential of marine green microalgae Tetraselmis sp. to biodegradate DCF.

 

CONCLUSIONS

  • Acute toxicity results with Tetraselmis sp. showed a EC50 48h to DCF of 60.42 mg/L (R2 = 0.98);
  • Chronic toxicity results indicate values to DCF of LOEC of 100 mg/L and NOEC of 10 mg/L in 48 h;
  • Biodegradation tests evidenced the Tetraselmis sp. can be used to degrade and remove DCF from a marine medium, even though the efficiency was low.

 

19 January 2023 - 12:30 CET

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