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abstract 836

COMPARATIVE ADSORPTION OF LEVODOPA FROM AQUEOUS SOLUTION ON DIFFERENT GRANULAR ACTIVATED CARBONS

Author(s): Isariebel Quesada- Penate, carine Julcour-Lebigue, Ulises-Javier Jauregui-Haza, Anne-Marie Wilhelm, Henri Delmas
JULCOUR-LEBIGUE Carine,WILHELM Anne-Marie and DELMAS Henri:bLaboratoire de Génie Chimique 5 rue Paulin Talabot - BP 1301-31106 Toulouse cedex 1,France QUESADA- PEÑATE Isariebel and JÁUREGUI-HAZA Ulises-Javier: Center for Pharmaceutical Chemistry Calle 200 y 21. Atabey, Playa. Apdo. 16042, C. Habana, Cuba

Keyword(s): Levodopa, pharmaceutical wastewaters, adsorption isotherms, activated carbon

Article:

Poster:

Session: Poster session 2

AbstractGranular activated

carbon filtration has been successfully used in wastewater and drinking water treatment plants, for removal of

different pollutants and it is the most efficient conventional treatment method for the purification of water

contaminated by other pollutants like pesticides. Levodopa is a drug used to treat Parkinson disease, a progressive

condition in which the part of the brain responsible for controlling movement stops functioning properly.
In the

present study, is reported, for the first time, the adsorption of levodopa from water solution onto activated carbon.

The activated carbon was characterized using the low temperature nitrogen adsorption. The equilibrium isotherms at

25 oC were determined. Six models (Langmuir, Jovanovic, Freundlich, Jovanovic-Freundlich, Redlich-Peterson and

Radke-Prausnitz) were evaluated to fit the experimental data. The characteristic parameters for each isotherm were

calculated and the selection of the most adequate model was performed using the Fisher’s test. From the obtained

experimental results, the adsorption process can be well described with Jovanovic-Freundlich model (q=369,21

mg/g, a=0,0042 and =0,52) with an average standard error of estimation of 3,62 %.

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COMPARATIVE ADSORPTION OF LEVODOPA FROM AQUEOUS SOLUTION ON DIFFERENT GRANULAR ACTIVATED CARBONS