Prof. Isabel Santos, Dr. Romain Forestier, Dr. Begüm Erol Forestier, Dr. Alain Françon, Dr. Araceli Muela Garcia
Centre de Recherches Rhumatologiques et Thermales d’Aix-les-Bains
OPINION ARTICLE
Nowadays, the biochemistry research on Rheumatoid Arthritis (RA) and Sulfur Bath have found that many physiological elements modulate several pathways such as neuroendocrine and immunogenic systems. This dynamic process regulates different biological activities related to bio-chemical-physical powers, although they are still not completely understood, especially concerning genomics of groundwater. Furthermore, we have a « functional » immunogenic system, receptor of internal and external signals, and the core of complex interactions between the patient, the RA, the skin and sulfur water. We think it would be interesting to brainstorm about all these interactions based on current knowledge…